在因COPD恶化而住院的患者中识别肺栓塞的挑战
Rufang Li1, Jie Zeng1, DanXiong Sun1
1Department of Pulmonary and Critical Care Medicine, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology. Kunming 650022, China.
Respiratory medicine and research
|July 7, 2024
概括
慢性阻塞性肺病 (AECOPD) 的急性恶化中的肺栓塞 (PE) 与较高的D-二次数水平,深静脉血栓塞 (DVT) 和简化威尔斯分数2或以上有关. 这些因素有助于识别风险增加的患者.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 关键的护理关键的护理
背景情况:
- 慢性阻塞性肺病 (AECOPD) 的急性恶化对全球健康构成重大风险.
- 肺栓塞 (PE) 是AECOPD住院期间常见且严重的并发症,会对患者的预后产生负面影响.
研究的目的:
- 为了比较有PE和没有PE的AECOPD患者之间的临床数据.
- 为了确定与AECOPD患者PE发展相关的临床因素.
主要方法:
- 对191名AECOPD患者进行了回顾性病例控制研究 (2018年1月至2021年12月).
- 对疑似PE的放射性检查;没有PE的患者作为对照.
- 用单变量和多变量逻辑回归分析来确定PE的独立预测因素.
主要成果:
- 在AECOPD和AECOPD-PE组之间没有观察到显著的人口差异.
- 在AECOPD-PE组中,D-二聚合物度升高,简化的威尔斯得分≥2,以及下肢深静脉血栓症 (DVT) 显著增加.
- 多变量分析证实D-二次体,DVT和威尔斯分数是PE的独立预测因子,组合因子的AUC为0.729.
结论:
- D-二次数水平,下肢DVT的存在,以及简化的威尔斯分数≥2与AECOPD患者的PE风险增加有关.
- 这些发现提高了对AECOPD次要PE的临床理解,有助于风险分层和管理.
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