影响饮食进展的因素 细胞还原性手术 (CRS) 和高温腹腔内化疗 (HIPEC) 后的饮食进展
Allysha Stibbard1, Morgan Brown2, Rachel Pons2
1St George Hospital, Department of Nutrition and Dietetics, Level 2, Pritchard Wing, Kogarah, NSW, 2217, Australia; School of Medicine, Smart Foods Centre, Illawarra Health and Medical Research Institute, University of Wollongong, Building 32, Northfields Ave, Keiraville, NSW, 2500, Australia.
Clinical nutrition ESPEN
|July 7, 2024
概括
细胞还原性手术和高温腹腔内化疗 (CRS/HIPEC) 后缓慢的饮食进展 (SDP) 与更多的并发症有关. 优化营养,包括腹腔营养 (PN),可以改善腹癌患者的结果.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 腹膜癌症 (PC) 治疗包括细胞减小手术 (CRS) 和高温腹膜内化疗 (HIPEC).
- 术后营养对于恢复和预防营养不良等并发症至关重要.
- 了解影响饮食进展的因素是优化患者护理的关键.
研究的目的:
- 在CRS/HIPEC之后,确定与缓慢的饮食进展 (SDP) 相关的因素.
- 评估术后并发症对饮食进步的影响.
- 为改善PC患者营养摄入量的策略提供信息.
主要方法:
- 在2019年4月至2020年8月期间,对42名接受CRS/HIPEC治疗的患者进行了回顾性审计.
- 根据开始全液饮食 (在7天内或之后) 患者被分为快速饮食进展 (FDP) 和缓慢饮食进展 (SDP) 组.
- 统计分析比较了FDP和SDP组之间的患者特征,手术因素和术后并发症.
主要成果:
- 在SDP组 (20名患者) 经历了显著更多的胃肠道解,肠切除,延长的阴茎,并返回剧院.
- 在SDP组的患者的第一次排便时间更长,Clavien-Dindo得分更高 (≥IIIb).
- 亲肠道营养 (PN) 使用 (61.3%) 和更长的术后停留时间与SDP有显著的关联.
结论:
- 术后并发症与缓慢的饮食进展密切相关,患者接受CRS/HIPEC治疗PC.
- 及时启动营养支持,包括PN,对于改善术后结果至关重要.
- 加速饮食进展的策略可以减轻并发症,并促进这种患者群体的康复.
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