仔细观察胃肠道出血心力衰竭患者
Anas Zaher1, Jude ElSaygh1, Akram Midani1
1New York Presbyterian-Brooklyn Methodist Hospital/ Weill Cornell Medicine, 506 6th street, Brooklyn, NY 11215, United States.
患有心力衰竭和减少排气分数 (HFrEF) 的患者面临着显著的胃肠道出血 (GIB) 风险. 高龄,高BNP水平和使用抗凝血剂/抗血小板药物是该人口中GIB的主要危险因素.
科学领域:
- 心脏病学 心脏病学
- 胃肠病学 胃肠病学
- 内部医学 内部医学
背景情况:
- 胃肠道出血 (GIB) 的风险和导致心力衰竭的因素与减少喷射率 (HFrEF) 患者仍然未得到充分研究.
- 这项研究解决了HFrEF人口中关于GIB发病率和相关风险因素的知识差距.
研究的目的:
- 为了确定GIB在HFrEF患者的频率.
- 在这个队列中确定GIB的风险因素.
- 分析抗血小板和抗凝 agent剂的使用情况,并检查GIB.经历的HFrEF患者内镜检测结果.
主要方法:
- 一项回顾性队列研究分析了2021年11月至2023年8月期间670名急性HFrEF患者.
- 胃肠道出血 (GIB) 通过手动图表检查血,黑色素或血等症状来确定.
- 统计分析,包括独立的t测试,将GIB患者 (病例) 与没有 (对照) 患者进行了比较.
主要成果:
- 在670名患者中,134名 (20%) 患有GIB. 与对照组相比,病例年龄较大 (中位数为77岁与70岁),血红蛋白水平较低,入院BNP水平较高.
- 抗凝剂的使用在病例 (64%) 与对照 (42%) 中较高,抗血小板剂的使用在病例 (68%) 与对照 (52%) 中也更频繁.
- 上部内镜检查显示,GIB患者的食道炎,食道静脉炎,胃炎,胃和十二指肠的发病率较高. 结肠镜检查显示,在GIB组中,多和分泌腺瘤的患病率增加.
结论:
- 心力衰竭患者表现出高GIB的风险.
- 高龄和入院时BNP水平升高是HFrEF患者GIB的重要风险因素.
- 虽然抗凝剂和抗血小板剂的使用与出血风险增加有关,但联合疗法并没有进一步提高这种风险. 常见的内镜检查结果包括食管炎,胃炎,,分泌腺炎和结肠质.
更多相关视频
04:00Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
Published on: November 15, 2024
06:11Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
Published on: May 21, 2017
相关概念视频
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Esophageal Varices-I: Introduction
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Pathophysiology of Heart Failure
