浏览65年的洞察力:关于儿童功能性腹痛的经验教训
Shaman Rajindrajith1, Christopher Chiong-Meng Boey2,3, Niranga Manjuri Devanarayana4
1Department of Pediatrics, Faculty of Medicine, University of Colombo, Colombo 8, 00800, Western Province, Sri Lanka. shamanrajindrajith4@gmail.com.
European journal of pediatrics
|July 7, 2024
概括
儿童反复出现的腹痛仍然是一个挑战,新的研究强调了肠-大脑相互作用和心理因素. 心理干预表明,在功能性腹部疼痛障碍中,有望获得更好的长期结果.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 儿童心理学 儿童心理学
- 临床流行病学临床流行病学
背景情况:
- 65多年来,人们一直在研究儿童的反复腹痛,但其病因和治疗仍然很复杂.
- 功能性腹痛障碍影响全球13.5%的儿童,严重影响他们的生活质量,并导致心理问题.
- 患有持续症状的儿童可能会发展成人的疾病,如易怒肠综合征和心理障碍.
研究的目的:
- 在过去的65年里,全面审查有关儿童功能性腹痛的当前文献.
- 更新执业的临床医生关于儿科腹痛的最新证据.
- 探索对病理生理学的不断发展的理解和新的治疗策略.
主要方法:
- 对过去65年发表的研究进行系统的文献综述.
- 对流行病学数据,风险因素和临床结果的分析.
- 评估药理和心理干预的有效性.
主要成果:
- 功能性腹痛的生物学基础涉及复杂的肠-大脑相互作用,包括微生物组的改变,运动问题和心理功能障碍.
- 药理干预措施,如阿米特利普提林在一些试验中显示效果与安慰剂相当.
- 心理干预,如肠道导向的催眠疗法,在缓解症状和长期预后方面表现出有希望的结果.
结论:
- 关于儿童腹痛的未回答问题导致不必要的调查和医疗保健费用.
- 功能性腹部疼痛障碍可以持续到成年期,通常与易怒肠综合征和心理并发症同时发生.
- 未来的研究应该专注于阐明病理生理机制,并探索新的,特别是心理的治疗策略,以改善儿科健康.
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