一项纵向的多中心队列研究,评估尼泊尔持续性产后抑郁症妇女在婴儿神经发育延迟
Ashish Kc1, Jaya Chandna2, Ankit Acharya3
1School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Medicinargatan 18, Gothenburg, Sweden. ashish.kc@gu.se.
BMC medicine
|July 7, 2024
概括
母亲产后抑郁症显著增加了婴儿神经发育延迟的风险5.21倍,6个月. 对母亲抑郁症的早期干预对婴儿发育至关重要.
科学领域:
- 围产期心理健康问题
- 婴儿神经发育 婴儿神经发育
- 发育儿科 发育儿科
背景情况:
- 婴儿的神经发育受到母亲的心理健康和照顾的影响.
- 产后持续的母亲抑郁症状是一个关键问题.
研究的目的:
- 评估母亲在产后前3个月持续存在的抑郁症状对6个月婴儿神经发育的影响.
主要方法:
- 在1253对母婴婴儿的纵向队列研究中.
- 使用爱丁堡产后抑郁量表 (EPDS) 评估的母亲抑郁症状在7,45,90天.
- 在6个月时使用世卫组织婴幼儿发展 (IYCD) 工具评估婴儿神经发育.
主要成果:
- 7.5%的母亲有持续的抑郁症状;7.5%的婴儿表现出神经发育迟缓.
- 患有持续抑郁症的母亲的婴儿患神经发育迟缓的风险增加了5.21倍 (aRR,5.21;95% CI,3.17,8.55).
- 在运动,语言,一般行为和社会情感领域观察到显著的延迟.
结论:
- 持续的产后抑郁症与6个月的婴儿神经发育延迟风险更高有关.
- 延迟涉及所有评估的功能领域.
- 针对母亲抑郁症的预防性干预可以减轻婴儿发育迟缓.
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