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Updated: Jun 21, 2025

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EGR3通过诱导施万细胞样分化来抑制瘤的进展

Cai-Hong Chen1, Yang Chen1, Yi-Nan Li1

  • 1Tianjin Nankai University State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Tianjin, 300350, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|July 8, 2024
PubMed
概括

早期生长反应3 (EGR3) 驱使黑色素瘤细胞采用施万细胞特征,减少增殖和运动性. 一种针对EGR3的新型mRNA疫苗通过增强免疫反应和控制瘤生长,显示出对癌症治疗的希望.

关键词:
这是EGR3的EGR3.这是mRNA疫苗.黑色素瘤是一种黑色素瘤.斯万恩细胞样分化的细胞.

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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