脚SBP和脉冲波速度的逆侧差异:与发生心力衰竭和死亡率的关联
Daniela Charry1, Jing Xu2, Michelle L Meyer3
1Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, Texas.
Journal of hypertension
|July 8, 2024
概括
脚血压和脉冲波速度的反侧面差异与老年人死亡风险更高有关. 这些测量可以作为评估心血管健康的重要指标.
科学领域:
- 心血管医学 心血管医学
- 老年学是指老年学的学科.
- 血管生物学 血管生物学
背景情况:
- 臂部静脉血压 (SBP) 的反侧面差异表明潜在的心血管问题.
- 通过外围测量来评估血管健康对于预测不良结果至关重要.
研究的目的:
- 为了研究脚SBP,腕脉冲波速率 (baPWV) 和心脚脉冲波速率 (haPWV) 和心力衰竭和死亡风险的相对边差异之间的关系.
- 在老龄化人口中确定这些血管参数的预测值.
主要方法:
- 利用考克斯的比例风险模型分析了社区动脉样硬化风险研究 (平均年龄75岁) 的5077名参与者的数据.
- 评估结果包括发生心力衰竭,全因死亡率和心血管死亡率,平均随访时间为7.5年.
主要成果:
- 在脚SBP (≥15 mmHg),baPWV (>240 cm/s) 和haPWV (>80 cm/s) 和所有原因死亡率增加之间发现了显著的关联.
- 逆侧脚SBP差异 (≥15 mmHg) 和haPWV (>80 cm/s) 独立地与更高的心血管死亡率有关.
- 未经调整的分析表明,这些差异也与心力衰竭的更高风险有关.
结论:
- 脚SBP和脉冲波速度 (PWV) 的相反侧面差异是老年人死亡风险增加的重要指标.
- 常规评估这些外围血管测量可能会增加心血管风险分层.
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