在正常下泌尿道的婴儿中测定排泄压力:探索神经发育可能的影响
Mazyar Zahir1,2, Seyedeh-Sanam Ladi-Seyedian1,3, Masoumeh Majidi Zolbin1
1Department of Pediatric Urology, Pediatric Urology and Regenerative Medicine Research Center, Gene, Cell and Tissue Institute, Children's Hospital Medical Center, Pediatrics' Center of excellence, Tehran University of Medical Sciences, Tehran, Iran.
Neurourology and urodynamics
|July 8, 2024
概括
圣骨发育不良的婴儿,以较低的圣骨比率 (SR) 表示,具有显著更高的最大排泄压力 (P det. 马克斯) 的时间. 这一发现表明,婴儿的圣骨发育和膀功能之间存在联系.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 神经泌尿病学 神经泌尿病学
- 放射学 放射学是一门学科.
背景情况:
- 圣器发育不良,通过非正常的圣器比率 (SR) 确定,可能会影响婴儿的膀功能.
- 了解这种关联对于诊断和管理下尿道问题至关重要.
研究的目的:
- 为了研究交叉骨发育不充分 (subnormal SR) 和增加的最大解器空气压力 (P det. 在婴儿的最大) 婴儿.
- 要确定圣骨比率是否是P det升高的预测因素. 这是马克斯.
主要方法:
- 对45名婴儿进行了因先天性尿管皮层结口阻塞而进行皮叶造形手术的回顾性队列研究.
- 圣器比 (SR) 是从手术前排空囊电图 (VCUG) KUB 放射图计算的.
- 最大的驱动器空气压力 (P det. 最大) 通过上导管在手术内测量.
主要成果:
- 婴儿SR<0.74的婴儿表现出明显更高的P det. 最大 (167.5 ± 60.8 厘米H2O) 与那些SR≥0.74 (55.7 ± 17.9 厘米H2O) 的人相比.
- 尽管如此,SR仍然是P det的重要预测因素. 在调整年龄和性别后的最大值 (p < 0.001).
- 在SR<0.74组 (100%) 与SR≥0.74组 (70.6%) 相比,生理学上detrusor缩器失调 (PDSD) 的发生率更高.
结论:
- 腰椎神经部发育不良,以低于正常的神经部比率来表示,与关节-解器失调有关.
- 这种失调可以导致生理学上的detrusor关节失调 (PDSD) 和升高的P det. 在婴儿的max.婴儿.
- 测量SR可以作为婴儿潜在的膀功能障碍的一个有价值的指标.
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