相关实验视频
Updated: Jun 21, 2025
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
14.3K
感染性内心炎的临床微生物学风险因素在病毒群中 streptococci 细菌血症
Jiyeon Bae1, Jae Hyeon Park2, Minkyeong Lee1
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
The Journal of antimicrobial chemotherapy
|July 8, 2024
概括
鉴定感染性内心炎 (IE) 风险因素在病毒群链球菌 (VGS) 血流感染 (BSI) 中至关重要. 关键预测因素包括心脏膜疾病,持续性细菌病和年轻年龄,指导心声回声学决策.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 微生物学 微生物学
背景情况:
- 对于对感染性内心炎 (IE) 患者进行回声心脏学诊断的最佳时间,病毒群链球菌 (VGS) 血流感染 (BSI) 仍然不确定.
- VGS BSIs可能会导致严重的并发症,需要清楚地了解相关风险.
研究的目的:
- 在患有VGS BSI的患者中确定IE的独立风险因素.
- 在这个患者群体中提供数据驱动的建议,以明智地使用心声回声学.
主要方法:
- 在2013年1月至2022年12月期间,在首尔国立大学医院进行了一项回顾性研究.
- 分析了患有VGS和营养变异性链球菌BSI的患者,不包括单个阳性血液培养物和多微生物感染.
- 使用多变量逻辑回归和灵敏度分析来确定独立的风险因素.
主要成果:
- 在845个VGS BSI病例中,分析了349个,揭示了86个IE病例 (24.6%).
- 对IE的独立风险因素包括心脏膜疾病 (aOR,14.14),持续性细菌病 (aOR,5.12) 和年龄较小.
- 缺乏固体癌症 (aOR,0.26) 或血液恶性瘤 (aOR,0.04) 和感染虫群细菌 (aOR,6.50) 也是显著的.
结论:
- 年龄较小,心脏膜疾病,持续性细菌病,不存在恶性瘤和VGS虫群BSI是IE的独立风险因素.
- 应考虑基于这些已识别的临床微生物学风险因素进行心声学评估.
相关概念视频
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.1K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.1K
01:26Factors Affecting the Risk of Infection
11.6K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.6K
01:22Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
01:20Infection
7.8K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.8K
01:30Bacterial Signaling
32.0K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
32.0K
01:18Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K