Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Impact of preoperative radiotherapy on the risk of postpancreatectomy haemorrhage and major morbidity after resection of pancreatic adenocarcinoma including arterial divestment or arterial resection.

BJS open·2026
Same author

Morphological characterization of a novel model of steatohepatitis in the <i>FAH</i><sup><i>-/-</i></sup> pig.

Veterinary pathology·2026
Same author

Living Paired Exchange Donation: Unlocking New Horizons in Kidney Transplantation.

Mayo Clinic proceedings·2025
Same author

A Rare Surgical Case of a Posterior Rectus Sheath Hernia Causing Small Bowel Obstruction.

Cureus·2025
Same author

Diclofenac and acetaminophen dim the acute-phase response but amplify expression of the iron regulator hepcidin in liver cancer cells.

Cell systems·2025
Same author

Lower extremity extracorporeal distal revascularization (LEEDR) as a novel approach to limb salvage following prolonged ischemia.

Scientific reports·2025

相关实验视频

Updated: Jun 21, 2025

Decellularization and Recellularization of Whole Livers
09:24

Decellularization and Recellularization of Whole Livers

Published on: February 4, 2011

22.0K

使用脱细胞化支架的肝脏组织工程:当前的进展,挑战和机遇.

Kamal H Hussein1,2,3, Boyukkhanim Ahmadzada1,2, Julio Cisneros Correa1,2

  • 1Department of Surgery, Mayo Clinic, Rochester, MN, United States.

Bioactive materials
|July 8, 2024
PubMed
概括
此摘要是机器生成的。

全肝生物工程为肝脏供体短缺提供了一个有希望的解决方案. 这种组织工程方法涉及脱细胞化和再细胞化,以创建功能性的生物工程肝脏用于移植.

关键词:
胆道重建 胆道重建生物工程肝脏生物工程肝脏脱细胞化 脱细胞化再细胞化是重细胞化尾细胞再形成的过程

更多相关视频

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.1K
3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis
06:46

3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis

Published on: February 25, 2022

1.9K

相关实验视频

Last Updated: Jun 21, 2025

Decellularization and Recellularization of Whole Livers
09:24

Decellularization and Recellularization of Whole Livers

Published on: February 4, 2011

22.0K
Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.1K
3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis
06:46

3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis

Published on: February 25, 2022

1.9K

科学领域:

  • 再生医学是一种再生医学.
  • 组织工程是组织工程.
  • 器官生物工程器官生物工程

背景情况:

  • 末期肝病需要肝移植,但供体器官稀缺造成了显著的差距.
  • 全肝生物工程成为解决器官短缺问题的潜在解决方案.

研究的目的:

  • 审查肝脏脱细胞化和再细胞化技术的进展.
  • 确定阻碍生物工程肝脏临床应用的障碍.

主要方法:

  • 审查脱细胞化策略,以删除细胞成分,同时保持细胞外基质 (ECM).
  • 分析使用适当细胞重建肝脏结构的再细胞化方法.
  • 在体内移植模型的概述,用于评估生物工程肝功能.

主要成果:

  • 在脱细胞化和再细胞化技术方面取得了重大进展.
  • 主要挑战包括ECM免疫性,脚手架制造标准化,细胞源选择和血管/胆道重建.

结论:

  • 克服生物工程肝脏发育方面的挑战对于临床翻译至关重要.
  • 生物工程肝脏有望满足移植需求并改善患者的治疗结果.