"使用网络分析模块化来分组健康代码系统,并在机器学习模型中降低维度"
Mohsen Askar1, Lars Småbrekke1, Einar Holsbø2
1Department of Pharmacy, Faculty of Health Sciences, UiT-The Arctic University of Norway, PO Box 6050, Stakkevollan, N-9037 Tromsø, Norway.
Exploratory research in clinical and social pharmacy
|July 8, 2024
概括
网络分析模块化有效地将医疗保健代码组合起来,提高了在药房研究中的机器学习模型性能. 这种方法提高了复杂的医疗保健数据的预测准确性和临床解释性.
科学领域:
- 计算生物学是一种计算生物学.
- 医疗信息学 医疗信息学
- 机器学习是机器学习.
背景情况:
- 机器学习 (ML) 模型与像ICD,ATC和DRG这样的高维的医疗保健编码系统 (HCS) 斗争.
- 编码这些代码是一个挑战:平衡缩小维度与信息保存.
研究的目的:
- 评估网络分析的模块化性,以分组HCSs.
- 改进医疗保健和药房研究中的ML模型的编码过程.
主要方法:
- 使用MIMIC-III数据集的ICD-9代码构建了一个多病症网络.
- 模块化检测算法将代码分组,并通过四种策略 (模块化,层次,CCS,二进制编码) 进行性能比较,以预测ICU再接收.
- 用物流回归,SVM和梯度提升机来评估模型性能.
主要成果:
- 模块化编码在ML模型中显著优于二进制编码,提高了准确性,AUC,回忆和精度.
- 与其他方法相比,基于模块化的分组通常显示出更高的性能,特别是AUC和精度.
- 在各种ML算法中观察到性能改进.
结论:
- 模块化编码通过减少维度而保留关键信息来提高药房研究中的ML模型性能.
- 这种方法是多功能,适用于层次和非层次的HCS,临床相关,并提高模型的可解释性.
- 一个Python包可用于支持模块化编码在未来研究中的应用.
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