典型的压力波形可以区分呼吸道崩模式的睡眠呼吸暂停患者:试点研究
Ravi R Shah1, Ahmad F Mahmoud2, Raj C Dedhia3
1Department of Otolaryngology-Head and Neck Surgery Henry Ford Health + Michigan State University Detroit Michigan USA.
OTO open
|July 8, 2024
概括
喉压力记录可以识别阻塞性睡眠呼吸暂停 (OSA) 的上呼吸道崩模式. 这种方法对评估低分泌神经刺激器 (HGNS) 植入的候选人有希望.
科学领域:
- 睡眠医学 睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医疗器械 医疗器械
背景情况:
- 阻塞性睡眠呼吸暂停 (obstructive sleep apnea,OSA) 是一种常见的睡眠障碍,其特点是经常出现上呼吸道崩.
- 像DISE这样的当前诊断方法可能是侵入性的,可能无法完全捕捉动态的气道变化.
- 确定特定的崩模式对于定制治疗至关重要,包括低分泌神经刺激.
研究的目的:
- 为了确定喉压力记录是否可以在OSA患者中区分各种上呼吸道崩模式.
- 评估喉压力记录与适合下神经刺激器 (HGNS) 植入器之间的相关性.
主要方法:
- 一个涉及25名OSA患者的前景病例系列.
- 同时的药物诱导睡眠内镜 (DISE) 和跨鼻喉压力记录.
- 根据地点,范围和方向,以及压力波形特征 (形状,振幅,斜率) 的崩模式的分类.
主要成果:
- 鼻腔波形形状与口腔崩程度相关 (P=.001).
- 口腔腔波形形状与崩地点 (P<.001) 和方向 (P=.019) 相关.
- 压力波形特征与崩程度和HGNS候选的有利模式有关 (P=.043,P=.004).
结论:
- 明显的喉压力波形与OSA中的特定上呼吸道崩模式有关.
- 喉压力测量是一种有价值的工具,有可能在评估睡眠手术候选人中增强DISE,特别是在HGNS.
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