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脑外内质细胞瘤:对文献的系统审查

Lucca B Palavani¹, Atharva Bapat², Sávio Batista³

¹Department of Medicine, Max Planck University Center, São Paulo, Brazil.

Asian journal of neurosurgery

|July 8, 2024

概括

外骨内血细胞瘤 (EMIP) 是罕见的,通常会影响. 放射治疗单独或与手术一起是常见的,但新的组合显示出更好的结果的希望.

科学领域:

神经学神经学
在瘤学瘤学.
病理学病理学病理学

背景情况:

外骨髓性血细胞瘤 (EMP) 涉及骨髓外的血细胞瘤.
内EMP (EMIP) 是一个鲜为人知的,罕见的表现.
关于EMIP的特点和管理的文献有限.

研究的目的:

分析人口人口统计,瘤位置,类型,治疗和内EMP的结果.
系统地审查有关EMIP的现有文献.
确定EMIP的常见差异诊断和有效的治疗策略.

主要方法:

按照PRISMA指南进行系统的文献审查.
搜索了PubMed,Embase,Scopus,Cochrane和科学网. 这是一个很大的问题.
包括25项研究,涉及84名被诊断患有内血细胞瘤的患者.

主要成果:

诊断时的平均年龄为57.25岁,57%是女性.
最常见的位置:大 (29.7%),额叶 (18.9%).
放射治疗 (RT) 是主要治疗方法;仅RT (17.8%) 和手术+RT (19%) 是常见的. 死亡率为48%.

结论:

骨是EMIP最常见的部位.
冠状瘤和脑膜瘤是关键的差异诊断.
RT占主导地位;新型组合疗法显示出提高疗效和安全性的潜力.

关键词:

冠状动脉瘤 (chordomas) 是一种状动脉瘤.额外骨髓性血细胞瘤.内血细胞瘤是什么血细胞瘤血细胞瘤一个人的血细胞瘤.

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