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估计慢性病患者中二次性甲状腺功能障碍症的全球患病率
Yichao Wang1,2, Jiaye Liu1,2, Yiqiao Fang1,2
1Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Frontiers in endocrinology
|July 8, 2024
概括
慢性病中的二次性甲状腺功能障碍 (SHPT) 影响全球近一半的患者. 这种情况在南亚,特别是中国最常见,突出了提高认识和管理策略的关键需求.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 与二次性甲状腺功能障碍症 (SHPT) 有关,这是一种与增加发病率和死亡率相关的疾病.
- 在CKD患者中,SHPT对不良健康结果有显著的贡献.
研究的目的:
- 进行元分析以确定慢性病患者中SHPT的全球患病率.
- 综合现有的关于CKD中SHPT患病率的数据,以告知临床和公共卫生战略.
主要方法:
- 从创立到2023年11月,在多个数据库 (Embase,Medline,Web of Science,Cochrane,Google Scholar) 进行了全面的文献搜索.
- 确定了与CKD相关的SHPT患病率的研究,并使用具有逻辑转换的随机效应模型计算了聚合患病率.
主要成果:
- 分析包括了21项研究,涉及110,977名患者.
- 由于CKD导致的SHPT的估计全球患病率为49.5%.
- 患病率因地区而异,南亚 (84.36%) 和中国 (85.14%) 的患病率最高.
结论:
- 与CKD相关的SHPT是全世界非常普遍的疾病.
- 提高意识和有针对性的治疗干预措施对于初级保健医生,医疗保健专业人员和卫生当局至关重要.
- 解决CKD中SHPT的高患病率对于改善患者的治疗结果和降低死亡率至关重要.
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