良性发性位置性和甲状腺疾病之间的关联:系统性审查和元分析
Cyntia Machado Lima1, Daniel Felipe Fernandes Paiva2, Ana Paula Corona3
1Postgraduate Program in Health Sciences, Faculty of Medicine, Universidade Federal da Bahia, Salvador, BA, Brazil.
International archives of otorhinolaryngology
|July 8, 2024
概括
良性发性位置性 (BPPV) 是常见的,但其原因尚不清楚. 这项研究发现了哈西莫托甲状腺炎和BPPV之间的显著联系,尽管没有甲状腺功能低下.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 良性发性位置性头 (BPPV) 是一种普遍存在的外围前庭性疾病,其病因不完全理解.
- 甲状腺疾病越来越多地被认为是BPPV的潜在促成因素.
- 调查这些关联对于理解BPPV的多样化起源至关重要.
研究的目的:
- 系统地审查和分析检查BPPV与甲状腺疾病之间的关联的流行病学研究.
- 为了确定特定的甲状腺疾病,如甲状腺功能低下症和哈希莫托甲状腺炎,是否与BPPV有关.
主要方法:
- 一个系统的审查和对PubMed,科学网络,Embase,Cochrane图书馆和Scopus的研究进行元分析.
- 包括的研究调查了BPPV和甲状腺疾病之间的关联.
- 分析使用了一个二分法模型,使用Mantle-Haenszel统计,赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 七项研究符合系统审查标准;四项提供了用于元分析的数据.
- 定性分析表明,这些研究来自欧洲和亚洲,主要是病例控制设计.
- 分析发现甲状腺功能低下症和BPPV之间没有关联,但哈希莫托甲状腺炎和BPPV之间有统计学显著的关系.
结论:
- 分析表明,BPPV和哈希莫托甲状腺炎之间存在潜在的关联.
- 需要进一步的研究来确认和阐明观察到的关系.
- 了解这种联系可能会为BPPV病原性提供新的见解.
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