在中国的痴呆病发病率的地理差异:一个地理空间分析
Yixuan Liu1,2, Xinyuan Gao1,2, Yongjin Zhang1,2
1Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510000, China.
The Lancet regional health. Western Pacific
|July 8, 2024
概括
中国的痴呆症患病率显示出显著的地理差异,北方患病率较高,南方患病率较低. 需要有针对性的区域战略来解决高血压和听力障碍等风险因素,以有效预防痴呆症.
科学领域:
- 老年学与公共卫生
- 流行病学 流行病学
- 空间分析 空间分析
背景情况:
- 痴呆症在中国带来了重大的健康和社会挑战.
- 目前缺乏省级痴呆症流行数据,阻碍了针对性的干预措施.
- 痴呆症患病率的地理差异被怀疑但未得到充分量化.
研究的目的:
- 为了估计中国各省的痴呆症患病率.
- 为了确定高和低痴呆病发病率的地理集群.
- 分析痴呆症风险因素的省级变化.
主要方法:
- 利用来自中国健康与退休长度研究 (CHARLS 2018) 的50岁以上17,176名成年人的数据.
- 调整到2020年中国人口普查,以提高代表性.
- 应用了贝叶斯条件自回归 (CAR) 模型,使用空间变化的系数来估计患病率和风险因素关联.
主要成果:
- 2018年,省级痴呆症患病率从2.62%到13.53%不等.
- 确定了中国北部的高痴呆症流行群和中国东部和南部的低流行群.
- 观察到痴呆症与高血压和听力障碍等危险因素之间的关联在各省有显著的差异.
结论:
- 在中国各地存在痴呆症患病率和风险因素影响的地理空间差异.
- 北部省份呈现高高的痴呆症群体,而南部省份呈现低低的痴呆症群体.
- 针对特定地区的痴呆症预防和治疗策略,解决高血压和听力损失等因素至关重要.
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