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在癌症免疫疗法中的"通用"T细胞受体工程T细胞的基于脂质体的 in situ抗原修饰策略

Qin Wang1, Rui Peng2, Haoyue Qi1,3

  • 1The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School Nanjing China.

MedComm
|July 8, 2024
PubMed
概括

这项研究引入了一种新型的脂质体输送系统,用于T细胞受体 (TCR) 工程T细胞疗法,通过使癌细胞上的人工抗原表达能够增强固体瘤治疗.

关键词:
纽约-ESO-1T细胞受体 (TCR) 工程T细胞疗法纽约-ESO-1 提供抗原.抗PD-1抗体是一种抗体.胃癌 胃癌 是一种胃癌.脂质体组是什么? 脂质体组是什么?

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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