Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Lidocaine Versus Amiodarone in Patients With Shockable Out-of-Hospital Cardiac Arrest: A Target Trial Emulation.

Critical care medicine·2026
Same author

Targeted Degradation of NETs in Lupus with DNASE1L3 Deficiency.

The New England journal of medicine·2026
Same author

Recombinant human diamine oxidase prevents histamine-induced hypoxia, shock and death in guinea pigs.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2026
Same author

Critical evaluation of the key mediators causing life-threatening symptoms during human anaphylaxis.

Drug discovery today·2026
Same author

Endovascular thrombectomy with or without intravenous thrombolysis in large-vessel ischemic stroke: an updated meta-analysis.

Scientific reports·2026
Same author

Effects of an early restrictive versus liberal fluid strategy on long-term patient-centered outcomes in sepsis-induced hypotension: an open-label, randomized controlled trial.

American journal of respiratory and critical care medicine·2026

相关实验视频

Updated: May 11, 2026

High Throughput Sequential ELISA for Validation of Biomarkers of Acute Graft-Versus-Host Disease
09:00

High Throughput Sequential ELISA for Validation of Biomarkers of Acute Graft-Versus-Host Disease

Published on: October 31, 2012

15.8K

在急性免疫反应中进行血小板造影:一项前性试点研究.

Calvin Lukas Kienbacher1, Christian Schoergenhofer2, Gerhard Ruzicka1

  • 1Department of Emergency Medicine, Medical University of Vienna, Vienna, Austria.

Research and practice in thrombosis and haemostasis
|July 8, 2024
PubMed
概括

通过血栓等级学测量的最大溶解 (ML) 与急性免疫反应的严重程度相关. 升高的ML和高纤维素分解表明更严重的过敏反应和血管.

关键词:
血液凝固 血液凝固纤维化解是一种纤维化解.免疫学模型 免疫学模型血小板结晶学 血小板结晶学 血小板结晶学组织等离子体激活剂激活剂

更多相关视频

A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry
04:32

A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

Published on: June 5, 2019

7.6K
Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
06:28

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

6.8K

相关实验视频

Last Updated: May 11, 2026

High Throughput Sequential ELISA for Validation of Biomarkers of Acute Graft-Versus-Host Disease
09:00

High Throughput Sequential ELISA for Validation of Biomarkers of Acute Graft-Versus-Host Disease

Published on: October 31, 2012

15.8K
A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry
04:32

A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

Published on: June 5, 2019

7.6K
Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
06:28

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

6.8K

科学领域:

  • 免疫学 免疫学 免疫学
  • 血液学 血液学 血液学
  • 紧急医疗 紧急医疗

背景情况:

  • 纤维素溶解的生物标志物在急性免疫反应中升高,如过敏反应和血管.
  • 纤维素分解与疾病严重程度之间的直接关联尚不清楚.

研究的目的:

  • 调查最大溶解 (ML),纤维素分解的测量,和急性免疫反应的严重程度之间的关联.
  • 为了确定通过血栓等级学测量的ML是否可以预测患有急性免疫反应的患者的疾病严重程度.

主要方法:

  • 招募了急性免疫反应的患者,并对其临床严重程度进行了分级.
  • 在入院时,最大溶解率 (ML%) 通过血栓形成显微镜 (EXTEM和APTEM测试) 确定.
  • 精确的后勤回归被用来分析ML%与疾病严重程度之间的关联,以及过纤维素分解的存在.

主要成果:

  • 在较高的ML%和症状严重程度增加之间发现了显著的关联 (OR,1.07;P = .003).
  • 在6名患者中检测到过敏纤维素溶解 (ML>15%),并与严重症状强烈相关 (OR,17.59;P = .02).
  • 随着反应的严重程度,D-二聚体,三酶和免疫球蛋白E的水平也在增加.

结论:

  • 通过血栓形成显微镜量化的最大溶解 (ML) 是与急性免疫反应的严重程度相关的重要生物标志物.
  • 血栓等级图可以帮助评估过敏反应和血管的严重程度.