一个多站点随机对照试验的方法和基线特征,评估基于正念的复发预防与同行支持一起,以改善对阿片类药物使用障碍药物的坚持
Mercy Ngosa Mumba1,2, George Tongi Mugoya2,3, Rebecca S Allen4
1Capstone College of Nursing, University of Alabama, Tuscaloosa, AL, United States.
Frontiers in psychiatry
|July 8, 2024
概括
这项研究结合了基于正念的复发预防 (MBRP) 和同行支持,以改善对阿片类药物使用障碍 (MOUD) 药物的坚持. 与传统的12步方便相比,这种综合方法在提高MOUD遵守方面表现出有希望.
科学领域:
- 成 药物 药物 药物 药物
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 对阿片类药物使用障碍 (MOUD) 的药物是有效的,但在启动和坚持方面面临挑战.
- 最佳的OUD治疗方法是将药物治疗与心理治疗相结合.
- 同行指导和MBRP在OUD治疗中显示了个人的好处.
研究的目的:
- 评估结合MBRP和同行支持 (MiMP) 对MOUD坚持的协同效应.
- 为了比较MiMP与增强的12步便利化 (TSF) 协议的有效性.
- 探索二次结果,包括复发率,渴望和心理健康指标.
主要方法:
- 进行了一项多站点随机对照试验.
- 参与者在每周的小组会议中接受了为期12周的手动MiMP或增强的TSF干预.
- 主要结局是MOUD的坚持;次要结局包括复发,渴望,抑郁,焦虑,压力,生活质量和痛苦的灾难化.
主要成果:
- 参与者的年龄从21岁到77岁不等 (平均44.5岁).
- 人口统计数据显示,性别和城市/农村分布几乎平等.
- 大多数参与者被认定为白人 (77.9%),并且有一些大学教育.
结论:
- 该研究结合了MBRP和对OUD治疗的同行支持,解决了并发性精神健康问题.
- 手动化协议和对生理测量 (皮质醇反应性) 的评估增加了创新.
- 这种综合方法可能会在MOUD坚持方面提供协同改进.
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