通过TGFβR信号传递,Lrba参与IgA+B淋巴细胞的分化

José Mizael Flores-Hermenegildo1,2, Felipe de Jesús Hernández-Cázares1, Daniela Pérez-Pérez2,3

  • 1Departamento de Biomedicina, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), Ciudad de México, Mexico.

PubMed
概括

蛋白质Lrba控制转化生长因子β受体 (TGFβR) 在B细胞中的信号传递,影响IgA的产生. 尔巴缺乏导致IgA+B细胞和血细胞的增加,这表明IgA在调节IgA稳态中的作用.

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