重症患者缺:对临床结果的影响
Pradeep K Suruli1, Pradeep Rangappa1, Ipe Jacob1
1Department of Critical Care Medicine, Manipal Hospital Yeshwantpur, Bengaluru, IND.
Cureus
|July 8, 2024
概括
缺乏症在重症患者中非常普遍,影响了研究中86%的患者. 尽管缺乏很常见,但在这个ICU队列中,缺乏与疾病严重程度或较差的患者结果无关.
科学领域:
- 关键护理医学 关键护理医学
- 营养科学 营养科学
- 微量元素的新陈代谢
背景情况:
- 是一种重要的微量元素,对许多酶功能和器官系统健康至关重要.
- 关于严重病患者群体中缺乏的患病率和临床影响的研究有限.
- 了解状况对于优化重症监护室 (ICU) 患者护理至关重要.
研究的目的:
- 为了前性地评估严重病情的成年患者中缺乏症的患病率.
- 研究缺乏症与临床结果之间的关联,包括ICU死亡率和住院时间.
- 探索含量与疾病严重程度得分之间的关系 (APACHE II,SOFA).
主要方法:
- 一项前性观察性研究,对50名临床重症成人患者进行了第三级护理重症监护室.
- 根据血清水平分类的患者:正常 (≥71μg/dl) 和缺乏 (≤70μg/dl).
- 缺陷进一步分类为轻度,中度或严重;结果包括ICU死亡率,通风持续时间,AKI,RRT和血管压缩剂使用.
主要成果:
- 缺乏症非常普遍,在86% (43/50) 的患者中发现.
- 在缺乏 (33%) 和正常水平 (43%) 的ICU患者之间,ICU死亡率没有显著差异.
- 缺乏的患者年龄较大 (平均年龄为69岁而不是49岁),并且显示出对替代疗法 (RRT) 需求增加的趋势.
结论:
- 缺乏症在重症患者中非常常见.
- 这项研究表明,这种群体中的缺乏与疾病严重程度无关,也不能预测较差的结果.
- 需要进行更大规模的研究来证实这些发现,并确定关于在严重疾病中的作用的最终结论.
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