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相关概念视频

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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三维相位解析功能性肺磁共振成像

Filip Klimeš1, Andreas Voskrebenzev2, Frank Wacker2

  • 1Institute of Diagnostic and Interventional Radiology, Hannover Medical School; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Centre for Lung Research (DZL); klimes.filip@mh-hannover.de.

Journal of visualized experiments : JoVE
|July 8, 2024
PubMed
概括

三维相位解析功能性肺部 (PREFUL) MRI 评估整个肺部的通风动态. 这种无辐射技术与肺功能测试有很强的相关性,并为患者友好的肺评估提供了经济有效的替代方案.

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科学领域:

  • 肺部医学 肺部医学
  • 放射学 放射学是一门学科.
  • 医疗成像医学成像

背景情况:

  • 肺部MRI提供了使用各种技术的无辐射肺呼吸评估.
  • 超极化气体MRI和富里埃分解 (FD) MRI是关键的方法.
  • 最近的进展重点是提高FDMRI的分辨率和整个肺部的能力.

研究的目的:

  • 引入和评估新的3D PREFUL MRI技术,用于动态,全肺通风评估.
  • 将3D PREFUL的性能与现有的方法和肺功能测试进行比较.
  • 评估3D PREFUL用于肺透气评估的可重复性和临床实用性.

主要方法:

  • 开发了一种3D PREFUL MRI采集,使用一堆星星破坏的梯度回声序列与金色角度增量.
  • 采用压缩传感用于在大约40个呼吸阶段的图像重建.
  • 注册了呼吸器分辨率图像和提取的通风参数进行分析.

主要成果:

  • 3D PREFUL在健康志愿者和COPD患者的呼吸参数和肺功能测试测量之间显示出强烈的相关性.
  • 该技术实现了可接受的间扫描可重复性,表明了重复评估的可靠性.
  • 与2D PREFUL相比,3D PREFUL提供全肺覆盖,空间分辨率提高.

结论:

  • 3D PREFUL MRI是一种有前途的无辐射技术,用于全面评估肺呼吸.
  • 它提供了一种成本效益和患者友好的替代方案,以超极化129XeMRI.
  • 这一进步使得能够详细评估整个肺部的动态通风.