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Updated: Jun 21, 2025

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肝脏高生物可用性是否会增强口服葡萄糖皮质类药物的效果,而不是皮下葡萄糖皮质类药物的效果?

Eva H van Geel1, Maarten Boers2, Linda Hartman3

  • 1Amsterdam Rheumatology and Immunology Center, Reade, Amsterdam, and Amsterdam Rheumatology and Immunology Center, Amsterdam University Medical Centers, Amsterdam, The Netherlands. e.h.vangeel@amsterdamumc.nl.

Clinical and experimental rheumatology
|July 8, 2024
PubMed
概括

低剂量的口服葡萄糖皮质类药物 (GC) 在降低红细胞沉率 (ESR) 方面并不比皮下GC更有效. 这表明系统度峰值,而不是高肝脏生物可用性,解释了口服GC在自身炎症性疾病中的有效性.

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