用贝兰塔马夫多丁治疗的患者的角膜毒性:如何改善和促进患者使用折射转移的随访?
Jason Chauvier1, Marie-Caroline Trone1,2, Philippe Gain1,2
1Ophthalmology Department, University Hospital, Saint-Etienne, France.
概括
用贝兰塔马布马福多丁治疗多发性骨髓瘤患者的折射性波动的监测可以帮助追踪角膜变化. 这种非侵入性方法有助于管理治疗副作用,并促进患者的随访.
科学领域:
- 眼科医生 眼科 眼科
- 在瘤学瘤学.
- 角膜疾病 角膜疾病
背景情况:
- 多发性骨髓瘤 (MM) 是一种流行的血液癌症.
- 贝兰他马布 (Belantamab mafodotin) 针对耐火性MM的B细胞成熟抗原进行向.
- 这种治疗可以导致角膜内微囊和折射性波动.
研究的目的:
- 评估监测折射率波动的有用性.
- 为了将这些波动与微囊状上皮细胞变化 (MECs) 的位置相关联.
- 改善MM患者的患者随访策略.
主要方法:
- 观察性,多中心研究.
- 从法国中心通过安全电子邮件收集的数据.
- 使用标准化数据收集表.
主要成果:
- 折射波动显示出近视转移与MEC位置 (从外围到中心) 相相关.
- 与中央MEC观察到的最佳校正视敏度 (BCVA) 降低,角质测量增加和心态测量增加.
- 结果与现有文献一致,突出了现实世界的变化.
结论:
- 折射波动监测是一种可重复的,非侵入性的选工具.
- 方便患者对角膜并发症的随访.
- 强调需要多学科的后续战略.
关键词:
这是一种B细胞成熟抗原.贝兰他马布 (Belantamab) 是一种马福多丁 (Mafodotin) 的药物.在Blenreprep中使用.结合抗体结合抗体是指结合的抗体.角膜毒性 角膜毒性 角膜毒性类似微囊的上皮细胞变化.骨髓瘤多样性 骨髓瘤多样性短视转移转移近视的人.更多相关视频
04:00Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
Published on: August 2, 2024
1.8K
05:46Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024
411
相关概念视频
Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment
1.7K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.7K
