关于乳头甲状腺癌复发的中间风险因素的重新分类:一项回顾性队列研究
Qiang Chen1, Xiuhe Zou1, Feng Liu1
1Department of Thyroid Surgery, West China Hospital, Sichuan University.
International journal of surgery (London, England)
|July 8, 2024
概括
中等风险的乳头甲状腺癌 (PTC) 的长期复发是罕见的. 结合原发性瘤和淋巴结风险因素,特别是超过5个转移性淋巴结,可以预测PTC患者的复发风险.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 有限的数据存在于中等风险的乳头甲状腺癌 (PTC) 的长期复发.
- 了解无复发生存 (RFS) 的风险因素对于患者管理至关重要.
研究的目的:
- 评估主要瘤和淋巴结 (LN) 风险因素对中等风险PTC中RFS的影响.
- 为了比较不同风险因子子子组和手术方法之间的RFS.
主要方法:
- 在2010年至2016年期间接受治疗的799名中等风险PTC患者的回顾性审查.
- 根据中间风险因素对子组进行分类.
- 调查和比较RFS的利率.
主要成果:
- 在中位数96个月的随访期间,在1.4%的患者中观察到结构性复发.
- 只有原发性瘤和只有LN的风险组之间没有显著的RFS差异.
- 组合的原发性瘤和>5个转移性LNs与更严重的RFS相关.
- 甲状腺叶切除术和全甲状腺切除术之间可比的6年RFS (99.6%对98.8%).
结论:
- 甲状腺叶切除术在中等风险的PTC中提供了与甲状腺全切除术相比较的RFS.
- 主要瘤因素和>5转移性LNs的组合预测了长期的结构性复发风险.
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