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有证据支持健康人群使用益生菌吗?
Daniel J Merenstein1, Daniel J Tancredi2, J Philip Karl3
1Department of Family Medicine, Georgetown University Medical Center, Washington, DC, United States.
Advances in nutrition (Bethesda, Md.)
|July 8, 2024
概括
益生菌在健康人群中显示出特定的健康益处,例如在使用抗生素时支持肠道功能和减少呼吸道感染. 然而,对于更广泛的预防性建议,需要更多的研究.
科学领域:
- 微生物学 微生物学
- 预防医学 预防医学
- 营养科学 营养科学
背景情况:
- 益生菌通常作为食品和食补充剂销售,用于一般健康维护.
- 与药物不同,益生菌不能声称可以治疗或治愈疾病.
- 本综述侧重于益生菌有益于一般健康人群的证据.
研究的目的:
- 审查健康人群中益生菌在预防感染 (尿道,阴道,胃肠道,呼吸道) 的有效性方面的证据.
- 评估益生菌对心血管健康风险因素的影响和减少抗生素使用.
- 评估益生菌特定预防性健康主张的证据.
主要方法:
- 现有科学文献的描述性审查.
- 专注于健康个体特定健康终点的疗效证据.
- 排除了诸如精神,牙或免疫健康等终点.
主要成果:
- 有足够的证据支持在使用抗生素期间使用特定的益生菌来支持肠道,并减少某些个体的呼吸道感染风险.
- 有证据表明,对一些预防性终点有潜在的益处,但对无条件的全民推却没有.
- 安全数据支持考虑特定的指示用途.
结论:
- 临床医生和消费者可以根据当前的证据考虑特定的益生菌用于某些适应症.
- 需要进行额外的研究,以建立更强有力的证据,证明益生菌在健康人群中的更广泛的预防性应用.
- 证据支持针对性的使用,而不是对所有预防终点的普遍建议.
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