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门诊患者的急性咳:是什么原因引起的,持续时间多长,不同病毒和细菌的严重程度有多大?
Mark H Ebell1, Dan J Merenstein2, Bruce Barrett3
1Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
概括
病原体的类型,无论是病毒还是细菌,都没有显著影响门诊患者下呼吸道感染 (LRTI) 的持续时间或严重程度. 这项研究分析了美国成年人LRTI的症状,持续时间和微生物学.
科学领域:
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
- 微生物学 微生物学
背景情况:
- 下呼吸道感染 (LRTI) 是常见的门诊疾病.
- 了解致病原体及其对症状持续时间和严重程度的影响,对于有效的患者管理至关重要.
研究的目的:
- 在门诊患者中描述LRTI的症状,持续时间和严重程度.
- 确定LRTI的微生物学,并将其与临床表现相关联.
主要方法:
- 一项前性队列研究招募了美国初级或紧急护理机构中出现咳和LRTI症状的成年人.
- 多重PCR被用于检测46种病毒和细菌. 通过日记和短信追踪症状的严重程度和持续时间长达28天.
主要成果:
- 病毒感染与更系统的症状有关,如发烧和肌痛,而细菌感染与有色有关.
- 平均咳持续时间约为16.4天,根据确定的病原体没有显著差异.
- 与细菌或混合感染相比,病毒感染的整体症状严重程度趋于较低.
结论:
- 在LRTI中确定的特定病原体不是症状持续时间或严重程度的显著预测因素.
- 这些发现与欧洲研究一致,表明LRTI呈现和结果的概括模式.
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