工人中潜在有毒元素的低水平与自我报告的健康结果有关
Fernanda Junqueira Salles1, Fredi Alexander Diaz-Quijano2, Maciel Santos Luz3
1Department of Environmental Health, School of Public Health, University of Sao Paulo, Av. Dr. Arnaldo, 715, Cerqueira Cesar, CEP 01246-904 Sao Paulo, SP, Brazil; The Human Exposome Research Group/ Expossoma e Saúde do Trabalhador - eXsat, School of Public Health, University of Sao Paulo, Av. Dr. Arnaldo, 715, Cerqueira César, SP, 01246-000, Brazil.
The Science of the total environment
|July 8, 2024
概括
非正式工人,特别是珠宝接工人,血液中含有,和等有毒元素的水平较高,与神经问题和血糖升高有关. 正式工作者没有表现出这些差异,突出了非正式职业暴露的风险.
科学领域:
- 环境健康 环境健康
- 职业医学 职业医学是专业的.
- 毒理学 毒理学 毒理学
背景情况:
- 职业接触有毒元素对健康构成重大风险.
- 潜在有毒元素 (PTE) 包括重金属,如,和.
- 了解不同工作环境中的PTE水平对于公众健康至关重要.
研究的目的:
- 为了评估巴西正式和非正式工人的PTE血度.
- 调查血液中PTE水平与健康结果之间的关联.
- 为了比较非正式工人,正式工人和对照组之间的PTE暴露和健康影响.
主要方法:
- 血液样本分析PTE (As,Cd,Cr,Cu,Hg,Mn,Ni,Pb,Sb,Sn,Zn) 使用三极四极诱导合等离子体质谱 (TQ ICP-MS).
- 生物化学测试包括血糖,胰岛素和脂质资料.
- 参与者填写了关于家庭风险和自我报告的发病率的问卷.
主要成果:
- 与对照人群相比,非正式工人血中 (Cd), (As) 和 (Pb) 度较高,血糖水平较高.
- 在正式工人和对照者之间没有发现PTE水平或健康标志物的显著差异.
- 血和的度与神经症状有关;血水平较高的患病率增加了2.3倍.
- 血液中的度与血糖水平有积极的关联.
结论:
- 非正式的职业接触PTE与增加不良健康结果的风险有关,包括神经问题和代谢障碍.
- 需要有针对性的监测和干预措施,以减少在非正式工作环境中的PTE暴露.
- 调查结果强调了解决弱势工人群体职业健康差异的重要性.
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