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Updated: Jun 21, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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合成,生物模拟和药理学评价具有抗高血压多目标作用的西米达衍生物

Abraham Gutiérrez-Hernández1, Samuel Estrada-Soto1, Carlos Martínez-Conde1

  • 1Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.

Bioorganic & medicinal chemistry letters
|July 8, 2024
PubMed
概括

研究人员开发了新的西米达衍生物作为潜在的抗高血压药物. 化合物1通过向血管新素II型1受体和通道,在老鼠中显著降低了血压.

关键词:
西米达 (Benzimidazole) 是一种一种生物异构体 生物异构体在高血压的高血压.多目标效应多目标效应

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