下肢变形静脉网络的性别患病率
Giulia Baldazzi1, Mirko Tessari2, Matilde Zamboni3
1School of Vascular Surgery, University of Ferrara, Ferrara, Italy; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
概括
多动脉的起源显示出基于性别的差异. 女人更容易患上来自前侧辅助沙发静脉 (AASV) 的静脉,而男性更容易从大沙发静脉 (GSV) 发展出来.
科学领域:
- 血管外科 血管外科
- 弗莱博学 (Phlebology) 是一种神经病学.
- 医疗成像医学成像
背景情况:
- 慢性静脉功能衰竭 (CVI) 影响着相当一部分人群.
- 了解CVI的性别特异性患病率及其解剖起源对于有针对性的治疗至关重要.
- 静脉网络可以来自各种表面静脉,包括大静脉 (GSV),前侧辅助静脉 (AASV) 和小静脉 (SSV).
研究的目的:
- 调查下肢静脉网络的性别流行情况.
- 为了确定与性别相关的静脉网络的特定静脉起源 (GSV,AASV,SSV).
- 探索终端 (TV) 状态与性别特异性静脉逆流模式之间的关联.
主要方法:
- 使用彩色多普勒超声波检查了1500名具有症状的CVI患者的3000个下肢.
- 排除了患有特异性疾病的患者,如血栓后综合征或静脉形.
- 数据分析的重点是确定患者性别相关的初级反流静脉 (GSV,AASV,SSV) 和终端 (TV) 状态.
主要成果:
- 由AASV反流 (单独或与GSV) 养的静脉网络在女性中明显更为普遍 (OR,1.96-1.84).
- 单独的GSV缺乏症在男性中明显更为普遍 (OR,0.54).
- 有能力的终端门 (TV +) 在女性中更常见,而无能力的门 (TV -) 在男性中更常见,与AASV和GSV反流模式相对应.
结论:
- 女性患者表现出来自AASV的静脉的更高患病率,特别是具有合格的终端 (TV+).
- 男性患者更容易出现GSV缺陷导致静脉静脉扩张的趋势,特别是在无能终端 (TV-) 的情况下.
- 这些发现表明男性和女性静脉发展的病理生理机制不同,可能涉及上升 (女性) 与下降 (男性) 逆流道.
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