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Updated: Jun 21, 2025

In Vitro Analysis of E3 Ubiquitin Ligase Function
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与VCP/p97相关的蛋白质是K48-K63分支 ubiquitin 链的结合剂和分支酶

Sven M Lange1,2, Matthew R McFarland3, Frederic Lamoliatte3

  • 1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK. smlange281@gmail.com.

Nature structural & molecular biology
|July 8, 2024
PubMed
概括

研究人员确定了关键蛋白质,并开发了研究分支无处不在链的工具. 这项工作揭示了分支酶,并表明K48-K63分支的乌比奎丁在涉及VCP/p97.7的细胞过程中的作用.

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