探索中年和老年中国成年人睡眠时间和癌症风险之间的关联:来自代表性队列研究 (2011-2020) 的观察结果
Yang Jiang1, Xinyue Gu2, Xiao Yang3
1Department of Pathology, Harbin Medical University Cancer Hospital, Harbin City, 150081, People's Republic of China.
BMC public health
|July 8, 2024
概括
睡眠时间短 (少于6小时) 与癌症风险增加有关,特别是对于消化和呼吸系统癌症. 睡眠时间较长也可能增加风险,但需要进一步研究.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 睡眠医学 睡眠医学
背景情况:
- 前性队列研究调查睡眠时间和癌症发病率.
- 9,996名参与者接受了平均9年的随访.
研究的目的:
- 为了检查睡眠时间和患癌症的风险之间的联系.
- 为了识别特定的癌症类型,可能与睡眠模式有关.
主要方法:
- 自我报告的睡眠时间和癌症发病率超过88,790人年.
- 考克斯的比例危险模型调整了混因子.
- 进行了年龄分层分析和相互作用分析.
主要成果:
- 短暂的睡眠 (<6小时) 显著增加了整体癌症风险 (HR: 1.27) 和消化/呼吸道癌症的风险 (HR: 1.41).
- 较长的睡眠时间 (>9小时) 显示了对癌症风险增加的非显著趋势.
- 长时间白天小睡 (>30分钟) 与女性癌症发病率 (p=0.041) 之间的显著相互作用.
结论:
- 睡眠时间短暂是癌症的潜在危险因素,特别是消化和呼吸系统癌症.
- 需要对更大的队列进行进一步的研究,以验证睡眠时间长和癌症风险之间的关联.
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