一个全国性的,多中心研究后内镜结直肠和上胃肠癌的协议:POET研究
William Xu1,2, Matthew James McGuinness2,3, Cameron Wells2,4
1Department of Surgery, Whangārei Hospital, Te Whatu Ora, Whangārei, New Zealand.
概括
这项研究确定了新西兰公立医院三年内结肠镜后结肠直肠癌 (PCCRC) 和结肠镜后上胃肠癌 (PEUGIC) 的发病率. 结果将为癌症监测在内镜检查后的质量改进计划提供信息.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 像结肠镜和上胃肠内镜这样的内镜手术对于诊断和管理胃肠疾病至关重要.
- 在这些程序后评估患癌症的风险对于患者安全和有效的查计划至关重要.
- 需要确定新西兰奥特拉新西兰的内镜后癌症的基线率.
研究的目的:
- 确定新西兰奥特亚罗亚的结肠镜后结肠直肠癌 (PCCRC) 的三年发病率.
- 确定新西兰奥特亚罗亚的内镜后上部胃肠道癌症 (PEUGIC) 三年发病率.
- 探索公共医院中PCCRC和PEUGIC的生存结果,原因,时间趋势和变化.
主要方法:
- 将采用回顾性队列研究设计.
- 数据将从参与STRATA协作网络的新西兰奥特亚罗亚所有公立医院收集.
- 将包括在内镜 (2010-2022) 后6至48个月内被诊断患有结直肠腺癌或胃食道癌的成年患者.
主要成果:
- 该研究旨在确定主要的结果指标:三年PCCRC率和三年PEUGIC率.
- 二次分析将描述生存,病因因素 (使用世界内镜组织分析系统),趋势和中心级变异.
- 结果将为内镜后的癌症监测提供关键的基准.
结论:
- 这项全国性的研究协议概述了一种强大的方法来评估新西兰的PCCRC和PEUGIC率.
- 生成的数据将作为未来研究和有针对性的质量改进工作的基础资源.
- 了解这些比率对于提高患者护理和优化内镜监测策略至关重要.
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