Vulvovaginal 候群病和 2 型糖尿病:全国性的回顾性队列研究
Emelie Brieditis1,2, Xinjun Li1, Kristina Sundquist1,2,3
1Center for Primary Health Care Research, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden.
Diabetes, obesity & metabolism
|July 9, 2024
概括
Vulvovaginal candidiasis (VVC) 可能是未来2型糖尿病诊断的信号,特别是在55岁以上的女性中. 该协会强调VVC是糖尿病风险的潜在早期指标.
科学领域:
- 内分泌学 在内分泌学.
- 妇科 妇科 妇科 妇科
- 流行病学 流行病学
背景情况:
- Vulvovaginal candidiasis (VVC) 是一种常见的妇科疾病.
- 需要进一步调查VVC和2型糖尿病等全身性疾病之间的潜在联系.
研究的目的:
- 调查是否 vulvovaginal candidasis (VVC) 在 2 型糖尿病的发展之前.
- 为了确定VVC诊断和随后的2型糖尿病诊断之间的时间间隔.
主要方法:
- 在瑞典 (2007-2018) 进行的一项回顾性全国性研究包括1,838,929名年龄在35-65岁之间的女性.
- 使用考克斯回归和倾向分数加权分析来评估VVC和2型糖尿病之间的关联,控制混因素.
主要成果:
- 与没有VVC的女性相比,有VVC病史的女性患2型糖尿病的发病率更高 (每1000人年4.05) (3.06每1000人年).
- 患有VVC的女性的2型糖尿病风险比为1.41 (调整) 和1.63 (倾向性评分加权).
- 这种增加的风险在55岁及以上的女性中尤为明显,每1000人年发生率为9.56.
结论:
- 在 vulvovaginal 候选症和2型糖尿病之间存在显著的时间关联.
- VVC可以作为未来糖尿病诊断的指标,特别是在绝经后的妇女中.
- 这些发现可以帮助临床医生在VVC治疗期间识别风险人群.
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