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牙周治疗中的根表面生物修饰:生物学理由和临床应用
Muhammad H A Saleh1, Debora R Dias2,3, Andrea Ravida2
1Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Periodontology 2000
|July 9, 2024
概括
牙周再生中的根表面生物修饰不会改善临床附着效果. 有证据表明,化学根调节与单独的机械仪器相比没有任何额外的好处,以获得更好的结果.
科学领域:
- 牙周病学 牙周病学
- 再生医学是一种再生医学.
- 生物材料是一种生物材料.
背景情况:
- 牙周再生疗法旨在恢复丢失的,牙周带和膜骨.
- 根表面作为伤口边缘在牙周再生中的关键.
- 理论上,根表面生物修饰通过去除涂抹层并促进凝块稳定性来增强组织附着.
研究的目的:
- 在再生性牙周治疗中提供根表面生物修饰的基于证据的评估.
- 评估其在骨内缺陷,裂缺陷和根覆盖程序中的作用.
主要方法:
- 对根表面生物修饰技术的现有证据进行系统审查.
- 对涉及化学根调节剂的研究进行分析.
- 当生物修饰用于骨移植,生物制剂,膜或结合组织移植时,对结果的评估.
主要成果:
- 根调节剂,单独或与其他再生材料相结合,在临床附着效益方面没有显示出临床优势.
- 经过审查的证据表明,将化学方法与机械根仪器相结合并没有优越的临床结果.
结论:
- 根表面生物修饰,包括化学修饰,似乎没有提高再生性牙周治疗中的临床附着效果.
- 目前的证据不支持常规使用化学根表面处理来改善牙周再生程序的结果.
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