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Updated: Jun 21, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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通过伪三组分反应,以多样性为导向的合成spiro[chromeno[2,3-b]pyridine-3,4'-pyrazole]衍生物

Wenyan Zhou1, Jiaman Lv1, Cunde Wang1

  • 1School of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting Street, Yangzhou 225002, P. R. China.

The Journal of organic chemistry
|July 9, 2024
PubMed
概括

一个新的单反应合成了新的spiro[chromeno[2,3-b]pyridine-3,4′-pyrazole]衍生物. 这种高效的方法产生了具有特定立体化学的复杂的spiropyrazolone-chromeno[2,3-b]pyridines.

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The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
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