孕妇在怀孕期间使用鼻烟作为无烟烟草和婴儿肺功能
Karen Eline Stensby Bains1,2, Ina Kreyberg3,4, Martin Färdig5,6,4
1Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
ERJ open research
|July 9, 2024
概括
孕妇在怀孕期间使用尼古丁产品,包括鼻和香烟,与婴儿肺功能减弱有关. 这项研究发现,婴儿仅接触鼻烟或吸烟时,低肺功能存在类似风险.
科学领域:
- 生殖健康 生殖健康
- 儿科肺病学 儿科肺病学
- 环境健康 环境健康
背景情况:
- 怀孕期间吸烟会对婴儿的呼吸系统健康产生不利影响.
- 其他尼古丁产品 (如鼻) 对婴儿肺功能的影响尚不清楚.
研究的目的:
- 调查怀孕期间使用无烟烟草 (snus) 是否会增加婴儿下肺功能风险.
- 为了确定这些关联是否因婴儿的性别而异.
主要方法:
- 分析了斯堪的纳维亚国家预防亚托皮肤炎和儿童过敏症出生队列 (1163名婴儿) 的数据.
- 3个月大时的潮流量测量.
- 回归分析探讨了与尼古丁暴露相关的风险 (任何,不包括鼻烟,吸烟) 调整为共变量.
主要成果:
- 10.3%的婴儿在子宫内暴露于尼古丁;71%的婴儿仅暴露于鼻,49%的婴儿暴露于吸烟.
- 在子宫内,尼古丁暴露与较高的下肺功能几率相关 (OR 1.63,95% CI 1.02-2.59).
- 在不含鼻烟 (OR 1.55) 和吸烟 (OR 1.79) 的暴露中观察到类似的风险;没有发现性别差异.
结论:
- 在子宫内暴露于鼻,类似于吸烟,可能会对婴儿的肺功能产生负面影响.
- 这些发现突出了母亲使用尼古丁产品对婴儿呼吸系统发育的潜在风险.
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