在日本,非结核性菌根性肺病增加了COPD和支气管切除的负担
Ping Wang1, Kozo Morimoto2, Naoki Hasegawa3
1Insmed Incorporated, Bridgewater, NJ, USA.
在日本,非结核性菌根性肺病 (NTM-PD) 显著增加了COPD或支气管切除症患者的住院病例. 这凸显了对这些脆弱的患者群体需要更好的NTM-PD管理策略的需要.
科学领域:
- 肺部医学 肺部医学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 非结核性菌根性肺病 (NTM-PD) 在日本非常普遍.
- 慢性肺炎和支气管切除在NTM-PD患者中很常见,使治疗复杂化.
- 有限的数据存在于日本患者的NTM-PD的额外负担与这些并发症.
研究的目的:
- 评估在日本先前患有慢性肺炎和/或支气管切除症的患者中NTM-PD的增加负担.
主要方法:
- 一项嵌套的病例控制研究使用了2015-2020年的索赔数据.
- 患有COPD/支气管切除症和NTM-PD (病例) 的患者与没有NTM-PD (对照) 的患者相匹配1:3.
- 在NTM-PD诊断1年后,医院住院情况使用单变量和多变量分析进行了比较.
主要成果:
- 与对照组相比,NTM-PD病例显示所有原因,呼吸系统相关和COPD相关住院病例显著增加.
- 例如,在COPD组中,20%的病例因各种原因住院治疗,而对照组只有13%.
结论:
- 在NTM-PD中,COPD和/或支气管切除症患者的住院费用大幅增加.
- 对于这些患者群体,日本迫切需要有效的NTM-PD管理策略.
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