脊髓损伤患者的睡眠和白天功能
Amira N Badr1, Salam Zeineddine2,3, Anan Salloum2,3
1Department of Physical and Occupational Therapy, Boston Children's Hospital, Boston, Massachusetts.
Research square
|July 9, 2024
概括
对于脊髓损伤 (SCI) 的退伍军人来说,失眠症状和睡眠质量差显著影响白天功能. 睡眠障碍的呼吸严重程度没有显示出类似的关联,强调失眠是干预的关键领域.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 康复医学 康复医学 康复医学
背景情况:
- 脊髓损伤 (SCI) 显著影响退伍军人的日常生活.
- 睡眠障碍在SCI患者中很常见,可能会影响他们的整体健康和功能.
- 了解睡眠呼吸障碍 (SDB),失眠和睡眠质量的特定作用对于改善这一群体的结果至关重要.
研究的目的:
- 研究睡眠呼吸障碍 (SDB),失眠症状和睡眠质量与SCI退伍军人的白天功能和生活质量之间的关系.
- 确定与睡眠相关的特定因素,这些因素有助于SCI的退伍军人功能障碍.
主要方法:
- 对38名患有SCI的男性退伍军人进行了横截面队列研究.
- 参与者完成了睡眠呼吸暂停严重程度 (呼吸暂停-呼吸暂停指数,AHI),失眠症状 (失眠严重程度指数,ISI),睡眠质量 (匹茨堡睡眠质量指数,PSQI),白天嗜睡 (埃普沃思嗜睡量表,ESS),疲劳,抑郁,功能 (脊髓独立测量,SCIM) 和生活质量 (WHOQOL-BREF) 的评估.
- 两变相关性被用来分析睡眠参数和功能结果之间的关系.
主要成果:
- 在睡眠呼吸暂停 (AHI) 的严重程度和日间功能测量之间没有发现显著的关联.
- 较高的失眠症状严重程度 (ISI) 与抑郁症 (PHQ-9),生活质量 (WHOQOL-BREF分级) 和功能 (SCIM) 的较差得分有显著的相关性.
- 较差的自我报告睡眠质量 (PSQI) 与疲劳增加 (FFS),抑郁症 (PHQ-9) 和生活质量下降 (WHOQOL-BREF分级) 有关.
结论:
- 失眠症状和睡眠质量差,但不是睡眠呼吸障碍的严重程度,与SCI退伍军人的白天功能和生活质量明显恶化有关.
- 失眠和睡眠质量差是潜在的可修改因素,有助于这一群体的功能缺陷.
- 对基于证据的失眠治疗对SCI患者的疗效进行进一步的研究是有必要的,以改善他们的功能结果.
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