对长期COVID和非长期COVID患者的贝叶斯生存分析:使用国家COVID队列协作 (N3C) 数据的队列研究
Sihang Jiang1, Johanna Loomba2, Andrea Zhou2
1School of Engineering and Applied Science, University of Virginia, 351 McCormick Rd, Charlottesville, 22904, VA, United States.
medRxiv : the preprint server for health sciences
|July 9, 2024
概括
长期COVID是一种已知的疾病,具有潜在的慢性疾病. 研究人员可以分析电子健康记录,研究长期COVID患者与非长期COVID患者的生存率.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 医疗信息学 医疗信息学
背景情况:
- 2020年开始的COVID-19大流行促使对感染的长期影响进行了广泛的研究.
- 疾病控制中心 (CDC) 在2021年10月为"后COVID-19状况,未指明"建立了一个特定的ICD-10-CM代码 (U09.9),承认长期COVID是具有潜在慢性后果的合法疾病.
研究的目的:
- 进行生存分析,比较长期COVID患者和非长期COVID患者.
- 为了利用汇总的电子健康记录 (EHR) 数据进行全面的患者队列研究.
主要方法:
- 使用国家COVID队列协作 (N3C) 数据资源.
- 汇总和协调来自美国各地不同临床组织的EHR数据.
- 对大量COVID-19阳性患者进行生存分析.
主要成果:
- 与非长期COVID患者相比,长期COVID患者的生存结果.
- 在COVID后的条件下确定影响生存的因素.
- 量化COVID-19对健康的长期影响.
结论:
- 长期COVID代表着一个重要的公共卫生问题,需要持续调查.
- N3C数据资源对推进长期COVID及其长期后果的研究起到重要作用.
- 生存分析为患有后COVID疾病的患者的预后和管理提供了关键的见解.
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