和分泌量及其与墨西哥成年人心血管疾病的相关性
Ismael Campos Nonato1, Kenny Mendoza1,2, Jorge Vargas Meza1,3
1Research Center of Nutrition and Health, National Institute of Public Health, Cuernavaca, Mexico.
Frontiers in nutrition
|July 9, 2024
概括
墨西哥成年人呈现高和低摄入量,增加心血管疾病的风险. 这突显了一个关键的公共卫生问题,需要饮食干预来改善心血管健康.
科学领域:
- 心血管健康的心血管健康
- 公共卫生营养 公共卫生营养
- 功能 功能 功能
背景情况:
- 心血管疾病 (CVD) 是全球和墨西哥的主要死亡原因.
- 高血压是心血管疾病的主要危险因素,影响大约50%的成年人群.
- 高 (Na) 和低 (K) 摄入量与心血管疾病有关,包括高血压 (BP).
研究的目的:
- 估计墨西哥成年人每天平均分泌的 (Na) 和 (K).
- 评估该人群中Na和K分泌与心血管疾病之间的关联.
- 评估与血压和功能相关的Na和K分泌量.
主要方法:
- 分析了2,778名墨西哥成年人 (20-59岁) 来自ENSANUT-2016调查的数据.
- 使用Tanaka配方从点尿样本估计Na和K的分泌量.
- 生物标志物的测量,包括葡萄糖,脂质 (总胆固醇,HDL,LDL) 和人体数据.
主要成果:
- 每天平均Na排泄量为3,354毫克/天,K排泄量为1,440毫克/天,Na-K比为2.4.
- 患有高血压的成年人比正常血压 (3,296毫克/天) 的成年人显示出更大的Na排泄量 (3,542毫克/天).
- 患有高血压的成年人排泄的K量比正常血压的成年人 (1357毫克/天) 多10% (1,534毫克/天). 患有中度功能下降的成年人分泌量减少了22%.
结论:
- 墨西哥成年人表现出高Na和低K排泄,对他们的心血管健康构成重大风险.
- 这些发现强调了需要公共卫生战略来解决饮食中Na和K不平衡的问题.
- 促进减少和增加摄入量的干预措施对于减轻墨西哥心血管疾病风险至关重要.
相关概念视频
Regulation of Sodium and Potassium
478
The regulation of sodium and potassium ion concentrations in the human body is a complex process governed primarily by hormones such as aldosterone, antidiuretic hormone (ADH), and atrial natriuretic peptide (ANP).
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily...
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily...
478
Antihypertensive Drugs: Potassium-Sparing Diuretics
511
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...
511
Roles of Electrolytes: Sodium and Potassium
348
Sodium plays a crucial role in maintaining fluid and electrolyte balance and overall bodily homeostasis. Sodium balance is primarily regulated by kidney function, which adjusts sodium elimination to match dietary intake and maintain proper electrolyte levels. Sodium is the most abundant cation in the extracellular fluid (ECF) and is found in salts such as sodium chloride (NaCl) and sodium bicarbonate (NaHCO3). Although cellular plasma membranes are relatively impermeable to sodium, its role in...
348
Disorder of Water Balance
346
Water balance disorders are medical conditions that occur when there is a deviation from the body's water volume or osmolarity, disrupting normal homeostasis and leading todehydration, hypotonic hydration, hyperhydration, edema, or water intoxication.
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
346
Heart Failure Drugs: Diuretics
362
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
362
Hypertension and Regulation of Blood Pressure
2.0K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.0K


