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在大学医院的炎症性肠病患者报告的表现
Ieva Renata Jonaitytė1,2, Vita Karpavičiūtė1, Gediminas Kiudelis1
1Department of Gastroenterology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Acta medica Lituanica
|July 9, 2024
概括
近一半的炎症性肠病患者患有皮肤和粘膜病变,性结肠炎和克罗恩病之间没有区别. 广泛的性结肠炎与这些肠外表现的更高患病率相关.
科学领域:
- 胃肠病学 胃肠病学
- 皮肤病学 皮肤病学
- 内部医学 内部医学
背景情况:
- 炎症性肠病 (IBD) 包括影响肠外器官的肠外表现 (EIMs).
- 关于IBD患者粘膜皮肤表现的患病率的数据有限.
- 这项研究旨在确定IBD患者皮肤和粘膜病变的频率及其与临床因素的关联.
研究的目的:
- 评估炎症性肠病 (IBD) 患者的粘膜皮肤病变的流行率.
- 研究粘膜皮肤表现和人口统计因素,IBD的临床特征和治疗方法之间的关系.
- 为了比较这些病变的发生在性结肠炎 (UC) 和克罗恩病 (CD) 之间.
主要方法:
- 一项前性研究涉及162名IBD门诊患者 (117名UC,45名CD).
- 患者填写了问卷,详细说明了人口统计信息,IBD病史以及过去或当前粘膜皮肤病变的存在.
- 数据分析的重点是病变的流行率和与疾病类型,程度和持续时间的相关性.
主要成果:
- 总的来说,48.1%的IBD患者报告了粘膜皮肤病变 (40.7%的皮肤,16.7%的口腔).
- 牛皮 (8.0%),结节性红斑 (5.6%),性皮肤炎/ (每个为3.7%) 是最常见的皮肤病变.
- 更广泛的UC与更高的皮肤病变频率相关 (p = 0.01),但病变发病率在UC和CD之间或疾病持续时间之间没有显著差异.
结论:
- 粘膜皮肤病变在IBD中很常见,影响了近一半的患者.
- 粘膜皮肤病变的存在和类型在UC和CD之间没有显著差异.
- 在UC的疾病程度是皮肤病变发展的重要因素,而疾病持续时间不是预测.
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