相关实验视频

Updated: Jun 21, 2025

Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration
10:43

Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration

Published on: May 19, 2016

6.7K

一个KIF1C-CNBP电机适配器复合体,用于将mRNA贩运到细胞突起

Konstadinos Moissoglu, Tianhong Wang, Alexander N Gasparski

    bioRxiv : the preprint server for biology
    |July 9, 2024
    PubMed
    概括

    研究人员发现信使RNA (mRNA) 如何到达细胞边缘. 蛋白质CNBP充当适配器,将mRNA与KIF1C电机蛋白连接在一起,以便沿着微管体运输,这对细胞迁移至关重要.

    更多相关视频

    Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy05:50

    Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy

    Published on: November 1, 2021

    2.3K
    Identification of Kinesin-1 Cargos Using Fluorescence Microscopy08:06

    Identification of Kinesin-1 Cargos Using Fluorescence Microscopy

    Published on: February 14, 2016

    7.9K

    相关概念视频

    Intracellular Signaling Affects Focal Adhesions01:17

    Intracellular Signaling Affects Focal Adhesions

    Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
    Some...
    2.7K
    Cytoskeletal Coordination in Cell Migration01:32

    Cytoskeletal Coordination in Cell Migration

    A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles correspondingly. These complex events are orchestrated by the dynamic cytoskeletal network comprising actin filaments, intermediate filaments, and microtubules. Cytoskeletal crosstalk — the direct and indirect communication between the different components — is crucial for this coordination. Direct communication involves various linker...
    4.7K
    Coat Assembly and GTPases01:33

    Coat Assembly and GTPases

    Vesicles incorporate different coat protein subunits in different cell locations, which changes the properties of the coat, such as the shape and geometry of the transport vesicles. Thus, vesicle coat proteins also play a significant role in cargo selection.
    Coat assembly depends on the local availability of phosphatidylinositol phosphates or PIPs and GTP-binding proteins. Adaptor proteins, which link the coat proteins to the membrane, bind to these PIPs and play a crucial role in controlling...
    3.5K
    Types of Membrane Protrusions01:28

    Types of Membrane Protrusions

    The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth. These membrane protrusions are a result of cytoskeletal rearrangement. The most  widely observed cell protrusions include lamellipodia, pseudopodia, filopodia, microvilli, invadopodia, and podosomes. These protrusions can be of two types — static or dynamic.
    The microvilli, an example of stable protrusions, are finger-like projections...
    2.8K
    Microtubule Associated Motor Proteins01:32

    Microtubule Associated Motor Proteins

    Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they associate with, the direction they move within the cell, and the type of cargo they transport. Motor proteins that associate with microtubules are known as microtubule-associated motor proteins. There are two families of microtubule-associated motor proteins —Kinesins and Dyneins. Both these proteins assist in the transport of cellular...
    7.9K
    Cell Motility through Blebbing01:16

    Cell Motility through Blebbing

    Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
    Blebbing Through the Matrix
    In multicellular...
    1.9K