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Updated: Jun 21, 2025

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MAPK酸酶-5是TGF-β通过一个依赖于JNK的通路进行信号传递所需的

Sam Dorry1, Sravan Perla1, Anton M Bennett1,2

  • 1Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA.

bioRxiv : the preprint server for biology
|July 9, 2024
PubMed
概括

中原激活蛋白激酶 (MAPK) 酸酶-5 (MKP-5) 通过调节转化生长因子-β (TGF-β) 信号传递,促进纤维化. MKP-5的失活阻断了TGF-β诱导的纤维基因激活,通过一个依赖于JNK的通路.

关键词:
基因激活的蛋白质激酶激酶是由基因激活的.细胞信号传递是细胞的信号传递.蛋白质酸酶是一种蛋白质酸酶蛋白质酸化和信号传导.

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