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Updated: Jun 21, 2025

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays
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Rab27b促进神经元中的溶酶体功能和α-synuclein清除

Kasandra Scholz, Rudradip Pattanayak, Ekkatine Roschonporn

    bioRxiv : the preprint server for biology
    |July 9, 2024
    PubMed
    概括

    Rab27b蛋白对于神经元中的α-synuclein (αsyn) 清除至关重要. 它的缺乏会损害 lysosomal 功能,在像帕金森病这样的 synucleinopathies 中促进 αsyn 聚合.

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