通过标准,基础设施和社区参与,共享来自人类瘤地图网络的数据
bioRxiv : the preprint server for biology
|July 9, 2024
概括
人类瘤图谱网 (HTAN) 数据协调中心 (DCC) 现在为公众提供了第一阶段的癌症数据. 该倡议促进了广泛的数据共享和利用,以促进癌症研究的进步.
科学领域:
- 在瘤学瘤学.
- 生物信息学是一种生物信息学.
- 数据科学数据科学数据科学
背景情况:
- 人类瘤图谱网 (HTAN) 旨在创建人类瘤的综合图谱.
- 有效的数据共享和利用对于推进癌症研究至关重要.
研究的目的:
- 描述HTAN数据协调中心 (DCC) 用于数据传播的基础设施和策略.
- 宣布公开HTAN第一阶段数据的可用性.
主要方法:
- 利用Synapse平台进行数据摄取和传播.
- 建立复杂癌症数据的数据标准和治理.
- 开发多种访问路线,包括门户,可视化工具和云平台.
主要成果:
- 从HTAN的第一阶段开始,公开可用的数据集和各种模式.
- 可通过HTAN门户,CellxGene,Minerva,cBioPortal和NCI癌症研究数据共享网站访问数据.
- 一个精简的基础设施,用于协调,标准化和传播癌症研究数据.
结论:
- HTAN DCC为管理和共享大规模癌症研究数据提供了一个成功的模型.
- 传播的数据和基础设施为科学界和类似的联盟提供了宝贵的资源.
- 这种方法支持更广泛地利用癌症数据进行研究和发现.
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