在患有骨关节炎的患者中,饮食炎症指数和虚弱之间的关系
Feng Zhao1, Fang Pan2, Jian Li3,4
1Second Ward of Department of Orthopedic Center, The People's Hospital of Feicheng, Shandong, China.
Annals of human biology
|July 9, 2024
概括
更高的饮食炎症指数 (DII) 与骨关节炎 (OA) 患者的虚弱风险增加有关. 这表明饮食改变可能会改善OA患者的生活质量.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 类风湿病学 类风湿病学
背景情况:
- 骨关节炎 (OA) 是一种普遍的慢性关节疾病,影响生活质量.
- 虚弱是OA进展的一个常见并发症.
- 饮食模式和OA中的脆弱性之间的联系尚未得到充分理解.
研究的目的:
- 研究OA患者的饮食炎症指数 (DII) 和虚弱之间的关联.
- 探索DII和脆弱之间的非线性关系.
- 为了检查炎症在DII-脆弱性关系中的调解作用.
主要方法:
- 分析了2530名OA患者在国家健康和营养检查调查 (NHANES) 中的数据.
- 根据报告的饮食摄入量计算DII.
- 后勤回归和受限制的立方线用于评估DII-脆弱性关系,并对炎症进行调解分析.
主要成果:
- 在同变量调整后,每一次DII标准偏差增加都与15%的脆弱风险增加有关 (OR = 1.15,95%CI = 1.03-1.28).
- 与DII < -1 (OR = 1.50,95%CI = 1.05-2.14) 的患者相比,OA患者的DII> 1具有明显更高的虚弱风险.
结论:
- 在OA患者中,DII与虚弱风险之间存在积极的关联.
- 饮食干预可以提供一种策略,以提高OA患者的生活质量.
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