动脉样硬化和艾滋病毒:探索心血管风险和管理
Matthew Seplowe1, Anjali Goyal2, Tolison Fowler3
1From the Department of Hospital Medicine, Mount Sinai Morningside, New York, NY.
Cardiology in review
|July 9, 2024
概括
艾滋病毒感染者面临较高的动脉样硬化心血管疾病 (ASCVD) 风险. 这篇评论探讨了艾滋病病毒.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗逆转录病毒疗法增加了艾滋病毒的存活率,将重点转移到诸如动脉样硬化心血管疾病 (ASCVD) 等慢性疾病上.
- 与一般人群相比,艾滋病毒感染者患心肌梗塞,中风和心力衰竭的发病率增加.
- 艾滋病毒感染及其治疗与传统的心血管风险因素相互作用,增加ASCVD风险.
研究的目的:
- 审查艾滋病毒感染者ASCVD的流行病学,病理生理学和管理.
- 探索艾滋病毒,抗逆转录病毒疗法和心血管健康之间的复杂关系.
- 综合当前的研究,为临床实践提供信息,并改善这一群体的心血管结果.
主要方法:
- 文献综述综合了临床试验数据.
- 对艾滋病毒和ASCVD的观察性研究的分析.
- 包括有关艾滋病毒相关心血管病理生理学的基础研究.
主要成果:
- 新出现的证据证实,艾滋病毒感染者患ASCVD的风险较高.
- 特定的心血管事件如心脏病发作,中风和心力衰竭更为常见.
- 艾滋病毒,治疗和风险因素的相互作用导致ASCVD负担增加.
结论:
- 对于艾滋病毒感染者来说,全面的心血管风险降低策略是必不可少的.
- 更好地了解与艾滋病毒相关的ASCVD对于改善患者的寿命和生活质量至关重要.
- 需要量身定制的医疗保健方法来管理ASCVD在HIV感染的背景下.
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