评估多发性硬化症葡萄牙患者的语音语言流性
Márcia França1, Cláudia Sousa1,2, Patricia Campos1
1Neuropsychology Unit of Department of Psychology, Centro Hospitalar Universitário São João Porto, Porto, Portugal.
与健康人相比,多发性硬化症 (MS) 患者的口语流性较低,其表现与教育水平有关. 多发性硬化症的认知能力下降是显著的,强调了口语流测试在评估中的作用.
科学领域:
- 神经心理学 神经心理学
- 神经学 神经学
- 认知科学 认知科学
背景情况:
- 执行功能障碍影响15-20%的多发性硬化症 (MS) 患者.
- 语言流利性测试,如单词列表生成 (WLG),对于评估MS的认知缺陷至关重要.
- 了解影响MS中WLG表现的因素对于准确的神经心理评估至关重要.
研究的目的:
- 为了比较多发性硬化患者和健康对照组之间的词汇列表生成 (WLG) 性能.
- 调查临床和人口因素对MS患者WLG表现的影响.
主要方法:
- 评估了109名多发性硬化患者和138名健康对照人群,使用葡萄牙语版本的WLG.
- 进行了额外的神经心理测试,包括神经心理测试的简短可重复电池 (BRBN-T) 和WAIS子测试.
- 评估语音流利性 (M,R,P),心理症状和认知疲劳.
主要成果:
- 多发性硬化症患者的WLG表现明显低于健康对照组.
- 在MS患者中,WLG表现与教育水平有显著的相关性.
- 多发性硬化症患者报告认知疲劳比对照组更高,但这与WLG表现无关.
结论:
- 多发性硬化症与语音口语流度的显著认知下降有关.
- 语言流和认知速度是MS神经心理评估中的重要指标.
- 教育水平似乎是影响MS口语流性缺陷的关键因素,比其他人口或临床变量更重要.
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