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Updated: Jun 21, 2025

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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在胸腺中自我调整:CD4与CD8谱系的承诺和调节性T细胞发育

Isabel Baldwin1, Ellen A Robey1

  • 1Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

The Journal of experimental medicine
|July 9, 2024
PubMed
概括

胸膜细胞在胸膜发育期间调整其T细胞受体 (TCR) 反应,使其能够存活并形成多样化的T细胞池. 一种序列选择模型解释了MHC特异性如何影响T细胞谱系选择和髓.

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